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Figure 2 | Molecular Cancer

Figure 2

From: Genetic alterations in pancreatic carcinoma

Figure 2

Interplay of the major genetic alteration in pancreatic carcinoma with the cell cycle. All four major genetic alteration, K-RAS, INK4a, TP53 and the TGF-β/SMAD4 tumor suppressor pathway, observed in pancreatic carcinoma, regulate directly or indirectly G1 progression, leading to E2F dependent S phase entry.

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Molecular Cancer

ISSN: 1476-4598