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Figure 2 | Molecular Cancer

Figure 2

From: Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

Figure 2

Complex I Activity. A flow cytometric assay of overall Complex I activity in normal human fibroblasts (GM38) and hypoxia-tolerant (M006x, M006xLo, M059K) and -sensitive (M010b) GBM cells. Changes in the relative ratio of dihydroethidium fluorescence after treatment of cells with rotenone are shown. Data shown for five or more separate experiments for each cell line. Error bars show mean ± s.d.

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