Genes Up-regulated in MSI-H Colorectal Cancer | ||
---|---|---|
Gene name | P value | Fold change |
Catenin (cadherin assoc. protein) beta 1 | 6.5 × 10-12 | 2.9 |
Interleukin 8* | 1.7 × 10-4 | 2.8 |
Granulysin* | 1.3 × 10-7 | 2.8 |
Caspase 2* | 6.0 × 10-8 | 2.4 |
Interleukin 24 | 0.004 | 2.3 |
Heat shock protein (HSP 110 family)* | 2.4 × 10-5 | 2.2 |
TP53 (Li Fraumeni)* | 2.5 × 10-4 | 2.2 |
Toll-like receptor 2 (TLR-2) | 1.9 × 10-4 | 1.9 |
Heat shock protein 70* | 3.5 × 10-6 | 1.8 |
Granzyme A | 0.001 | 1.7 |
Interleukin 1β | 0.004 | 1.7 |
Survivin | 0.001 | 1.6 |
Calreticulin | 2.9 × 10-5 | 1.6 |
Human Natural killer Cell enhancing factor | 0.001 | 1.6 |
CD68 antigen | 4.8 × 10-4 | 1.6 |
ICAM 1 (CD54) | 0.003 | 1.6 |
Interleukin 18 (interferon-gamma inducing factor)* | 0.003 | 1.5 |
Interleukin 7 | 4.6 × 10-4 | 1.5 |
Interleukin 15* | 0.002 | 1.5 |
Genes down-regulated in MSI-H colorectal cancer | ||
Gene name | P value | Fold change |
Insulin-like growth factor 2 (somatomedin A) | 1.9 × 10-5 | 4.3 |
TGFβ RII | 9.3 × 10-5 | 3.0 |
hMLH 1* | 6.7 × 10-5 | 2.4 |