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Table 2 Time to Cytopathic Effect Cells grown in 96 well plates were infected with ONYX-015 at the stated multiplicity of infection per row of cells. Values represent days until 50% of wells in a row showed cytopathic effect.

From: Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells

 

Multiplicity of Infection

Cell Line

0

1

10

100

300

9L-GFP

0

0

0

0

0

9L-HSP72

0

0

8

5

4

RT2-GFP

0

0

0

0

0

RT2-HSP72

0

0

0

4

4

DBTRG

0

6

4

-

-

NB4

0

5

4

-

-

293

0

2

1

-

-