Table 4 Epigenetic therapy agents

deoxycytidine analogs:

5-azacytidine, 5-aza-2-deoxycytidine, 1-β-D-arabinofuranosil 5-azacytosine, dihydro- 5-azacytidine

nucleic acid-based:

MG98 antisense oligonucleotide

cytidine deaminase analogs:

zebularine

non-nucleoside analogs:

(-)-epigallocatechin-3-gallate, procaine, procainamide, hydralazine

Histone deacetylase inhibitors

Small molecular weight carboxilates:

sodium butyrate, valproic acid, sodium phenylbutyrate and pivaloyloxymethyl butyrate

Hydroxamic acids:

SAHA, trichostatin A, SBHA

Benzamides:

CI-994, MS-275

Epoxyketones:

trapoxin B, 2-amino-8-oxo-9,10-epoxydecanoic acid

Cyclic peptides:

apicidin, depsipeptide

Hybrid molecules:

CHAP 31, CHAP50