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Table 1 Genes highly gained and overexpressed in huT78 cell line.

From: Identification of amplified and highly expressed genes in amplicons of the T-cell line huT78 detected by cDNA microarray CGH

Unigene ID

Gene Symbol

G

E

Log2(G)

Log2(E)

Cytogenetic Location

Gene

Hs.76884

ID3

1,857

2,343

0,893

1,228

1p36.13-p36.12

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

Hs.84981

XRCC5

2,04

4,044

1,029

2,016

2q35

X-ray repair complementing defective repair in Chinese hamster cells 5

Hs.162

IGFBP2

2,563

4,544

1,358

2,184

2q33-34

insulin-like growth factor binding protein 2

Hs.82793

PSMB3

1,794

3,874

0,843

1,954

2q35

proteasome subunit, beta type, 3

Hs.174007

VHL

3,119

2,044

1,641

1,031

3p26-p25

von Hippel-Lindau syndrome

Hs.55173

CELSR3

1,862

2,647

0,897

1,404

3p24.1-p21.2

cadherin, EGF LAG seven-pass G-type receptor 3

Hs.180145

HSPC030

1,777

2,947

0,829

1,559

3

HSPC030 protein

Hs.350266

ARGBP2

1,823

2,028

0,866

1,020

4q35.1

Arg/Abl-interacting protein ArgBP2

Hs.179565

MCM3

1,791

4,378

0,841

2,130

6p12

MCM3 minichromosome maintenance deficient 3

Hs.278589

GTF2I

1,886

2,379

0,915

1,251

7q11.23

general transcription factor II, i

Hs.167246

POR

2,007

2,609

1,005

1,384

7q11.2

P450 (cytochrome) oxidoreductase

Hs.61762

HIG2

1,885

3,152

0,915

1,656

7q32.2

hypoxia-inducible protein 2

Hs.274424

SAS

1,743

4,944

0,802

2,306

9p24.1-p23

N-acetylneuraminic acid phosphate synthase; sialic acid synthase

Hs.184793

DKFZP434F195

1,78

2,125

0,832

1,087

9

DKFZP434F195 protein

Hs.18910

POV1

1,78

3,702

0,832

1,888

11p11.2-p11.1

prostate cancer overexpressed gene 1

Hs.91877

THRSP

6,491

3,095

2,698

1,630

11q13.5

thyroid hormone responsive

Hs.180628

DNM1L

1,758

2,715

0,814

1,441

12p12.3

dynamin 1-like

Hs.76294

CD63

1,747

6,165

0,805

2,624

12q12-q13

CD63 antigen (melanoma 1 antigen)

Hs.247888

-

2,284

3,201

1,192

1,679

16

 

Hs.12303

SUPT6H

1,742

2,819

0,801

1,495

17q11.2

suppressor of Ty 6 homolog (S. cerevisiae)

Hs.296281

ILF1

1,754

3,146

0,811

1,653

17q25

interleukin enhancer binding factor 1

Hs.75716

SERPINB2

2,358

3,767

1,238

1,913

18q21.3

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2

Hs.8372

UQCR

2,046

2,916

1,033

1,544

19p13.3

ubiquinol-cytochrome c reductase subunit

Hs.661

NDUFB7

1,845

2,416

0,884

1,272

19p13.12-p13.11

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7

Hs.36992

-

4,848

3,213

2,277

1,684

19

 

Hs.250615

CYP2A7

1,778

3,718

0,830

1,895

19q13.2

cytochrome P450, subfamily IIA, polypeptide 7

Hs.356727

FKBP1A

1,918

4,022

0,940

2,008

20p13

FK506 binding protein 1A

Hs.305890

BCL2L1

6,941

11,508

2,795

3,525

20q11.21

BCL2-like 1, Bcl-X

Hs.273385

GNAS

1,764

2,059

0,819

1,042

20q13.2-q13.3

GNAS complex locus

Hs.284380

GGT1

1,784

2,762

0,835

1,466

22q11.23

gamma-glutamyltransferase 1

  1. Relation of 30 genes presenting genomic values ≥ 1.7 [log2(G) ≥ 0,8] and expression values ≥ 2 [log2(E) ≥ 1]; it represents gains above 4-fold and overexpression above 2-fold. In bold, genes located in amplicons. G, Genomic values; E, Expression values.
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Molecular Cancer

ISSN: 1476-4598