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Figure 4 | Molecular Cancer

Figure 4

From: Early expression of the Helicase-Like Transcription Factor (HLTF/SMARCA3) in an experimental model of estrogen-induced renal carcinogenesis

Figure 4

Combined immunolocalization of HLTF (A, C, E) and S100 protein (B, D, F) in DES-induced renal tumors. Immunostaining was performed with the ASE2 antiserum directed against HLTFMet123. A-B, C-D, E-F are corresponding fields in consecutive tissue sections. A-B, a cluster of neoplastic cells with HLTF immunoreactivity (A) appears S100 negative (B) (7 months of DES exposure). C-D, a small tumor negative for HLTF (C) exhibits S100 immunoreactivity (D) (7 months of DES exposure). E-F, mixed population of HLTF-positive (E) and S100-positive (F) cells in a medium size tumor (6 months of DES exposure).

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