Up-regulation of mRNA expression in human chromosomal region 12q21.1-q21.2 (patient counts with coordinate up-regulation). Grayscale cross-comparison plots of up-regulation patterns across patients (analogous to Figures 7, 10 and 13). View this plot in conjunction with Figures 15 and 17. Note, that many more patients show up-regulation as indicated by dark spots in this plot than down-regulation as indicated by dark spots in Figure 17. Over-expressed genes in this region comprise leucine-rich G-protein coupled receptor 5 (GPR49), HIV-1 rev binding protein 2 (HRB2), pleckstrin-homology-like domain family A member 1 (PHLDA1), nucleosome assembly protein 1-like 1 (NAP1L1), oxysterol binding protein-like 8 (OSBPL8), cystein- and glycine-rich protein 2 (CSRP2), E2F transcription factor 7 (LOC144455).