Figure 1
From: Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
Effects of apigenin on DNA synthesis in human pancreatic cancer cells. Apigenin caused significant concentration-dependent inhibition of DNA synthesis in all four cell lines studied: AsPC-1 [F (5,42) = 10.12, P < 0.0001; P = 0.01 with 50–100 μM]; CD18 [F (5,54) = 38.47, P < 0.0001; P < 0.01 with 12.5–100 μM]; MIA PaCa2 [F (5,72) = 8.698, P < 0.0001; P < 0.05 with 25 μM and P < 0.01 with 50–100 μM]; S2-013 [F (5,72) = 4.099, P < 0.0025; P < 0.05 with 50 μM and P < 0.01 with 100 μM]. Data represent results from at least three separate experiments each performed in triplicate, expressed as a percentage of control.