Figure 2
From: Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
Time-course effects of apigenin on cell number of human pancreatic cells. Apigenin significantly inhibited the increase in cell number of each cell line over time: AsPC-1, [F (5,59) = 10.65, P < 0.0001], P < 0.05 at 48 h and P < 0.001 at 72 h; CD18, [F (5,38) = 5.641, P < 0.0006], P < 0.001 at 72 h; MIA PaCa2, [F (5,65) = 6.127, P < 0.0001], P < 0.001 at 72 h; S2-013, [F (5,60) = 2.589, P < 0.0347], P < 0.05 at 72 h. Data represent results from at least three separate experiments each performed in triplicate, expressed as cell number/well. *= P < 0.05; **= P < 0.01; ***= P < 0.001 compared with control.