Table 1 Biomarkers identified by proteomics technologies in nasopharyngeal carcinoma
From: Nasopharyngeal carcinoma: molecular biomarker discovery and progress
Technology | Primary use | Biomarker |
|---|---|---|
Two-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry | Diagnosis | Fibronectin, Mac-2 binding protein, Plasminogen activator inhibitor 1 |
| Â | Signaling target | Annexin A2, Heat shock protein 27, Stathmin, Annexin I, Basic transcription factor 3, Porin |
| Â | Treatment response monitoring | Ceruloplasmin |
Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry and tandem mass spectrometry | Diagnosis | Inter-α-trypsin inhibitor precursor |
| Â | Treatment response monitoring | Platelet factor-4 |
| Â | Prognosis | Serum amyloid A |