Table 2 Downregulated genes after 5-aza-dC treatment of OVCAR cells. Chromosomal location and fold change in gene expression are shown for 5-aza-dC treated/untreated OVCAR 3 cells.
From: Identification of candidate methylation-responsive genes in ovarian cancer
RefSeq Transcript ID | Symbol | Gene Name | Chr. | Fold Change |
|---|---|---|---|---|
NM_0010138360 | MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 7p22 | -4.27 |
NM_004883 | NRG2 | Neuregulin 2 | 5q31 | -3.95 |
NM_001001331 | ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 3p25 | -2.88 |
NM_001719 | BMP7 | Bone morphogenetic protein 7 (osteogenic protein 1) | 20q13 | -2.56 |
NM_032932 | RAB11FIP4 | RAB11 family interacting protein 4 (class II) | 17q11 | -2.49 |
NM_014914 | CENTG2 | Centaurin, gamma 2 | 2q37 | -2.30 |
NM_013372 | GREM1 | Gremlin 1, cysteine knot superfamily, homolog | 15q13 | -2.28 |
XM_373734 | --- | Hypothetical LOC388388 | 3p13 | -2.28 |
NM_020761 | Raptor | Raptor | 17q25.3 | -2.26 |
NM_001031693 | HHLA3 | HERV-H LTR-associating 3 | --- | -2.20 |
NM_003598 | TEAD2 | TEA domain family member 2 | 19q13 | -2.18 |
NM_022773 | FLJ12681 | Hypothetical protein FLJ12681 | 16p13.3 | -2.18 |
NM_004389 | CTNNA2 | Catenin (cadherin-associated protein), alpha 2 | 2p12 | -2.09 |
XM_032996 | MICAL3 | Microtubule associated monoxygenase, calponin and LIM domain containing 3 | 22q11 | -2.08 |
NM_000620 | NOS1 | Nitric oxide synthase 1 (neuronal) | 12q24 | -2.06 |
NM_006567 | FARS2 | Phenylalanine-tRNA synthetase 2 | 6p25 | -1.20 |
NM_003466 | PAX8 | Paired box 8 | 2q13 | -1.99 |
NM_006613 | GRAP | GRB2-related adaptor protein-like | 17p11 | -1.97 |
NM_022138 | SMOC2 | SPARC related modular calcium binding 2 | 6q27 | -1.96 |
NM_017594 | DIRAS2 | DIRAS family, GTP-binding RAS-like 2 | 9q22 | -1.96 |
NM_021018 | HIST1H3F | Histone 1, H3f | 6p22 | -1.92 |
NM_004192 | ASMTL | Acetylserotonin O-methyltransferase-like | Xp22 | -1.92 |
NM_002412 | MGMT | O-6-methylguanine-DNA methyltransferase | 10q26 | -1.91 |
NM_001466 | FZD2 | Frizzled homolog 2 (Drosophila) | 17q21 | -1.91 |
XM_498471 | LOC147727 | Hypothetical protein LOC147727 | 19p13 | -1.90 |
NM_003562 | SLC25A11 | Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 17p13 | -1.88 |
NM_004565 | PEX14 | Peroxisomal biogenesis factor 14 | 1p36 | -1.87 |
NM_003955 | SOCS3 | Suppressor of cytokine signaling 3 | 17q25 | -1.87 |
NM_007037 | ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 | 11q24 | -1.85 |
NM_022479 | WBSCR17 | Williams-Beuren syndrome chromosome region 17 | 7q11 | -1.84 |