Figure 4
From: MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo
Ad-mda7 activates the caspase cascade in tumor cells. Activation of caspase-9, caspase-3 and PARP indicated by their cleavage products was observed in Ad-mda7-treated tumor cells but not in Ad-mda7-treated normal cells. β-actin was used as a loading control.