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Figure 2 | Molecular Cancer

Figure 2

From: Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers

Figure 2

In situ expression pattern of germ cell-related markers (MAGE-A4 and TSPY) in OGCTs and sex centromere material in interphase nuclei from OGCTs. MAGE-A4 in A1: Dysgerminoma and A2: In foetal ovary of GW 28 with strong expression in oogonia (lower left), and no expression in developing follicles (top right); TSPY in B1: Gonadoblastoma (Case PT-04) and B2: Dysgerminoma (Case PT-57). Scalebar = 25μm. Fluorescence in situ hybridisation of two different dysgerminomas with sex chromosome centromeres: C. Presence of X and Y chromosome material (Case PT-04) and D. Presence only of X chromosome material (Case PT-14). E-F: Inserts are control DAPI-only.

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Molecular Cancer

ISSN: 1476-4598