Figure 6
Localization of KCa channels in brain tumor tissues from xenogenic rat model and patients of lung cancer brain metastases. KCa channels (green) were localized in the endothelial cells of capillaries (red) in the tumor mass (A). In the contralateral side of brain, much less of KCa channel was detected in normal brain. (B). KCa channels are co-localized with von Willebrand factor, a marker of endothelial cells, in human tumor tissue of lung cancer brain metastases (C). Scale bar = 250 μm.