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Table 1 Differentially expressed genes in response to DDC overexpression*. The genes shown here are those whose expressions are increased (= 2) or decreased (= -2).

From: Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells

Genbank Acc Gene Symbol & Name DDC/CTRLs
Binding
BC016658 E2F7; E2F transcription factor 7 -13.60
AK024500 MICAL1; microtubule associated monoxygenase +7.92
BC009212 MTA1; metastasis associated 1 +9.50
NM_032943 SYTL2; synaptotagmin-like 2 -2.02
AK027128 ZNF277; zinc finger protein 277 -3.88
AK054916 ZNF333; zinc finger protein 333 +4.67
AK056666 ZNF488; zinc finger protein 488 +6.76
Binding and catalytic activity
NM_019885 CYP26B1; cytochrome P450, family 26, subfamily B, polypeptide 1 +4.29
NM_022819 PLA2G2F; phospholipase A2, group IIF +30.10
NM_004613 TGM2; transglutaminase 2 +2.10
AK022930 YME1L1; YME1-like 1 (S. cerevisiae) +21.40
Binding and signal transducer activity
NM_000796 DRD3; dopamine receptor D3 -4.28
U92285 GABRE;Gamma-aminobutyric acid (GABA) A receptor, epsilon +10.02
NM_004532 MUC4; mucin 4, tracheobronchial -6.39
AF070577 OPCML; opioid binding protein/cell adhesion molecule-like -3.87
NM_003728 UNC5C; unc-5 homolog C (C. elegans) +18.48
Catalytic activity   
AK055136 C2orf11; chromosome 2 open reading frame 11 +5.79
AK054688 PON2; paraoxonase 2 +6.99
Signal transducer activity
NM_005290 GPR15; G protein-coupled receptor 15 +7.47
AK026202 PTGDR; prostaglandin D2 receptor (DP) +5.26
Unclassified
AL110152 CD109; CD109 antigen (Gov platelet alloantigens) +6.20
NM_006408 AGR2; anterior gradient 2 homolog (Xenopus laevis) -5.31
NM_004312 ARR3; arrestin 3, retinal (X-arrestin) -8.08
NM_032149 C4orf17; chromosome 4 open reading frame 17 -6.81
AK024536 CADPS; Ca2+-dependent secretion activator +8.45
BC015117 DEPDC4; DEP domain containing 4 +7.83
AK057372 FLJ32810; hypothetical protein FLJ32810 -14.32
AF305616 TMEPAI; transmembrane, prostate androgen induced RNA +2.06
AK025272 Unkown +15.27
AK021730 Unkown +31.81
AF130053 Unkown +23.33
AL080106 Unkown +4.04
AK021569 Unkown +16.22
AK001133 Unkown +7.59
AK055083 Unkown +6.91
  1. *Bold indicated genes investigated further by RT-PCR