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Figure 3 | Molecular Cancer

Figure 3

From: Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma

Figure 3

Histological characteristics of trisomy 19 ependymoma: compactness with clear cut border (A, HE, 30×); rich branched capillary network (B, HE, 90×); perivascular pseudorosettes, always observed, but can be rare (C, HE, 250×); GFAP positivity, always observed (D, GFAP, 125×) but can be focal with large GFAP negative area (E, GFAP, 125×); focal region of tumoral cells with intra-cytoplasmic EMA dots, always found (F, EMA, 310×); Ki67 >10% (G, Ki67, 60×); neuronal markers: negative in the tumor, positive in the surrounding brain parenchyma (H: NF, 30× and I: Neu-N, 30×).

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