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Table 1 Effects of E2 on proliferation of MM cell lines*

From: Estrogenic or antiestrogenic therapies for multiple myeloma?

MM cell line

Response

Reference

ANBL6

Inhibition

[7]

ARH-77

No effect

[12]

KAS-6/1

Inhibition

[7]

KMM-1

Inhibition

[10]

LP-1

Inhibition

[11]

MM.1S/R

No effect

[4]

NCI-H929

Inhibition

[11]

OCI-My5

No effect

[12]

OPM-2

No effect

[11]

RPMI 8226

No effect

[4]

 

Inhibition

[10]

 

Inhibition

[11]

 

No effect

[12]

U266

Inhibition

[10]

 

Inhibition

[11]

 

No effect

[12]

  1. * Are presented in this table only authenticated MM (or at least well-characterized) cell lines indexed in [49]. In all cases, MM cell lines were treated in vitro with micromolar concentrations of E2 varying from 0.5 μM to 50 μM; various techniques were used to quantify cell proliferation: [3H]-thymidine incorporation, MTS reduction assay, cell number counting after trypan blue exclusion.
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Molecular Cancer

ISSN: 1476-4598