From: Role of PP2Cα in cell growth, in radio- and chemosensitivity, and in tumorigenicity
MCF7-wt | MCF7-si | ||||||
---|---|---|---|---|---|---|---|
Time (h) | RT Dose (Gy) | G0/G1 | S | G2/M | G0/G1 | S | G2/M |
24 | 0 | 61.3 ± 0.5 | 29.5 ± 1.1 | 9.2 ± 1.5 | 55.6 ± 0.5 * | 30.3 ± 0.4 | 14.2 ± 0.7 * |
2 | 68.3 ± 0.2 | 21.8 ± 0.4 | 9.9 ± 0.4 | 61.4 ± 1.3 * | 25.4 ± 1.1 * | 13.2 ± 0.5 * | |
4 | 71.6 ± 0.2 | 16.7 ± 0.2 | 11.7 ± 0.3 | 67.4 ± 6.2 * | 25.0 ± 5.7 * | 7.5 ± 0.9 * | |
6 | 70.9 ± 0.6 | 14.0 ± 0.4 | 15.1 ± 0.7 | 77.5 ± 0.9 * | 9.2 ± 1.5 * | 13.3 ± 0.6 * | |
12 | 66.8 ± 0.5 | 12.6 ± 0.3 | 20.6 ± 0.5 | 54.8 ± 0.9 * | 3.4 ± 0.3 * | 41.8 ± 0.8 * | |
48 | 0 | 61.5 ± 0.6 | 35.4 ± 1.4 | 12.7 ± 1.3 | 61.2 ± 1.8 * | 31.0 ± 1.2 * | 12.0 ± 0.4 |
2 | 62.9 ± 8.0 | 28.1 ± 5.5 | 9.0 ± 2.5 | 69.2 ± 0.4 | 21.4 ± 0.2 | 9.4 ± 0.4 | |
4 | 75.9 ± 6.7 | 15.8 ± 8.0 | 8.2 ± 1.3 | 77.9 ± 0.2 | 11.3 ± 0.4 | 10.8 ± 0.6 * | |
6 | 79.2 ± 1.0 | 7.4 ± 2.8 | 13.7 ± 3.4 | 74.4 ± 0.9 * | 5.8 ± 0.4 | 19.8 ± 1.3 * | |
12 | 55.3 ± 1.1 | 7.2 ± 3.7 | 37.3 ± 3.1 | 48.8 ± 0.4 * | 2.6 ± 0.4 | 48.6 ± 0.4 * | |
72 | 0 | 51.1 ± 1.3 | 42.4 ± 2.0 | 6.4 ± 1.2 | 54.0 ± 2.6 | 33.6 ± 0.2 * | 12.6 ± 2.9 * |
2 | 61.1 ± 0.3 | 26.6 ± 1.1 | 12.3 ± 1.0 | 61.9 ± 0.6 | 24.7 ± 0.1 * | 13.4 ± 0.6 | |
4 | 65.1 ± 1.7 | 21.2 ± 1.1 | 13.7 ± 1.3 | 66.2 ± 0.9 | 18.5 ± 0.9 * | 15.3 ± 1.5 | |
6 | 66.4 ± 0.6 | 14.7 ± 0.8 | 18.9 ± 0.9 | 68.4 ± 0.6 * | 13.8 ± 0.4 | 17.9 ± 0.1 | |
12 | 51.7 ± 0.7 | 8.1 ± 0.6 | 40.3 ± 0.2 | 54.9 ± 0.3 * | 6.4 ± 0.8 | 38.7 ± 0.2 * |