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Table 4 Overview over the experiments evaluating the tumorigenicity of the MCF7-wt and MCF7-si cells.

From: Role of PP2Cα in cell growth, in radio- and chemosensitivity, and in tumorigenicity

Experiment

Hormone Pellets

Matrigel

MCF-wt

MCF-si

1

-

-

0/10

0/8

2

+

-

0/8

1/8

3

-

+

0/10

0/10

4

+

+

4/8

9/10

  1. The number of tumors that had developed under control conditions (Exp. 1), upon the implantation of estrogen-containing hormone pellets (Exp. 2), upon the use of Matrigel (Exp. 3), and upon the combined implementation of estrogen-containing hormone pellets and Matrigel (Exp. 4) are presented.