Table 1 Epigenetically Regulated Genes Chosen for Expression Analysis
From: DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
Gene Designation | Unigene Number | Cancer-specific methylation1 | Gene Designation | Unigene Number | Cancer-specific methylation1 |
|---|---|---|---|---|---|
ADAM23 | Hs.591643 | CIMP | ISG15 | Hs.458485 | Breast |
APBA1 | Hs.592974 | Breast, CIMP | ISGF3G | Hs.1706 | Breast |
APBA2 | Hs.525718 | Breast, CIMP | KRTHB1 | Hs.584773 | Breast |
APC | Hs.158932 | Breast, CIMP | LCN2 | Hs.204238 | Breast |
BARD1 | Hs.591642 | Breast | LGALS3BP | Hs.514535 | Breast |
BF | Hs.69771 | Breast | MGMT | Hs.501522 | Breast, CIMP |
BRCA1 | Hs.194143 | Breast, CIMP | MINT31 | AF1355312 | Breast, CIMP |
C8orf4 | Hs.591849 | Breast | MLH1 | Hs.195364 | Breast, CIMP |
CCND2 | Hs.376071 | Breast, CIMP | MYB | Hs.531941 | CIMP |
CDH1 | Hs.461086 | Breast, CIMP | PARP12 | Hs.12646 | Breast |
CDKN1A | Hs.370771 | CIMP | PCDHGB6 | Hs.368160 | Breast |
CDKN2A | Hs.512599 | Breast, CIMP | PER1 | Hs.445534 | Breast, CIMP |
CDKN2B | Hs.72901 | CIMP | PGR | Hs.368072 | Breast, CIMP |
CEACAM5 | Hs.220529 | Breast | PRDM2 | Hs.371823 | Breast, CMP |
CEACAM6 | Hs.466814 | Breast | PRKCDBP | Hs.434044 | Breast, CIMP |
CST6 | Hs.139389 | Breast | RARα | Hs.137731 | Breast, CIMP |
CTCF | Hs.368367 | Breast, CIMP | RARβ | Hs.536687 | Breast, CIMP |
CYP1B1 | Hs.154654 | Breast | RASSF1 | Hs.476270 | Breast, CIMP |
DAPK1 | Hs.380277 | Breast, CIMP | RB1 | Hs.408528 | Breast, CIMP |
ESR1 | Hs.208124 | Breast, CIMP | SASH1 | Hs.193133 | Breast |
ESR2 | Hs.443150 | Breast, CIMP | SSAT | Hs.28491 | Breast |
G1P3 | Hs.523847 | Breast | SCNN1A | Hs.591047 | Breast |
GADD45A | Hs.80409 | Breast | SERPINB5 | Hs.55279 | Breast, CIMP |
GJB2 | Hs.591234 | Breast, CIMP | SFN | Hs.523718 | Breast, CIMP |
GNA11 | Hs.73797 | Breast | SIM | Hs.520293 | Breast |
GPC3 | Hs.567276 | Breast | ST18 | Hs.147170 | Breast |
GSTP1 | Hs.523836 | Breast, CIMP | STYK11 | Hs.515005 | CIMP |
HIC1 | Hs.72956 | Breast, CIMP | TFAP2A | Hs.519880 | Breast |
HOXD11 | Hs.421136 | Breast, CIMP | THBS1 | Hs.164226 | CIMP |
HS3ST2 | Hs.622536 | Breast, CIMP | TMEM45A | Hs.126598 | Breast |
IFI27 | Hs.532634 | Breast | TP73 | Hs.192132 | CIMP |
IGFBP5 | Hs.369982 | Breast | WT1 | Hs.591980 | Breast, CIMP |