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Figure 4 | Molecular Cancer

Figure 4

From: Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

Figure 4

Effect of different mutations of β-catenin on the expression of a reporter gene with the main 5'-enhancer of GS. Cells from the cell-line HuH7 were transfected with the reporter gene 'HIII/EV_pT81' containing the main GS 5'-enhancer together with different expression plasmids for β-catenin forms (compare legend to Fig. 3). Expression was compared to expression from pT81 in order to determine the factor of enhancement mediated by the mutants.

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Molecular Cancer

ISSN: 1476-4598