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Table 2 Differential effect of selected metabolites on the growth of Jurkat cells and normal lymphoblasts

From: Identification of metabolites with anticancer properties by computational metabolomics

   Jurkat Lymphoblasts
Metabolite c [μM]1 Growth [%] SEM [%]2 p-value Growth [%] SEM [%]2 p-value
Menaquinone 100 18.2 0.36 4.5 × 10-7 89.7 8.5 0.38
  50 40.3 1.15 2.0 × 10-7 109.9 5.8 0.23
Dehydroepiandrosterone 100 23.8 0.18 2.1 × 10-6 94.9 0.6 0.15
  50 83.2 0.23 2.0 × 10-3 130.8 6.9 0.020
Se-Seleno-L-methionine 100 41.0 0.67 1.0 × 10-7 79.3 5.8 0.028
  50 53.2 0.85 2.0 × 10-3 84.2 1.4 2.7 × 10-4
5,6-dimethylbenzimidazole 100 80.4 3.56 6.2 × 10-3 82.9 4.4 0.023
  50 87.8 1.41 0.021 97.4 1.9 0.037
  1. 1 Metabolite concentration.
  2. 2 Standard error of the mean.
  3. 3 Statistical significance of the observed effect on cell growth, as evaluated by two-tailed t-tests.