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Table 2 Differential effect of selected metabolites on the growth of Jurkat cells and normal lymphoblasts

From: Identification of metabolites with anticancer properties by computational metabolomics

  

Jurkat

Lymphoblasts

Metabolite

c [μM]1

Growth [%]

SEM [%]2

p-value

Growth [%]

SEM [%]2

p-value

Menaquinone

100

18.2

0.36

4.5 × 10-7

89.7

8.5

0.38

 

50

40.3

1.15

2.0 × 10-7

109.9

5.8

0.23

Dehydroepiandrosterone

100

23.8

0.18

2.1 × 10-6

94.9

0.6

0.15

 

50

83.2

0.23

2.0 × 10-3

130.8

6.9

0.020

Se-Seleno-L-methionine

100

41.0

0.67

1.0 × 10-7

79.3

5.8

0.028

 

50

53.2

0.85

2.0 × 10-3

84.2

1.4

2.7 × 10-4

5,6-dimethylbenzimidazole

100

80.4

3.56

6.2 × 10-3

82.9

4.4

0.023

 

50

87.8

1.41

0.021

97.4

1.9

0.037

  1. 1 Metabolite concentration.
  2. 2 Standard error of the mean.
  3. 3 Statistical significance of the observed effect on cell growth, as evaluated by two-tailed t-tests.