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Table 3 Chromosomal regions affected by DNA copy number alterations.

From: Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile

Chromosome

Affected cytobands

Region start-end positions (Mb)

Total length of aberrant regions (Mb)

No. of samples (%)

Regions of CN gain

    

4

p15.1-q13.1

29–62

5

11 (41%)

 

q26-q28.3

117–137

5

11 (41%)

5

p15.1-p14.1

17–29

10

11 (41%)

 

q11.2-q12.3

53–66

5

11 (41%)

 

q14.3-q21.3

84–105

12

11 (41%)

 

q23.1-q34

119–163

11

11 (41%)

7

p21.3-p21.2

8–14

5

11 (41%)

 

q21.11

81–85

4

11 (41%)

 

q31.31-q31.32

118–122

4

11 (41%)

11

p15.1-q12.1

21–57

11

11 (41%)

 

q14.2-q22.3

87–107

10

11 (41%)

12

q12-q15

35–69

10

11 (41%)

 

q21.31-q23.1

82–100

5

11 (41%)

14

q21.1-q21.3

41–48

4

11 (41%)

16

p11.2-q11.1

34–39

5

11 (41%)

19

p12-p11

24–28

4

12 (44%)

22

p13-p11.2

0–9

9

12 (44%)

Regions of CN loss

    

1

p36.32-p36.31

5–7

2

25 (93%)

 

p36.11

24–26

2

21 (78%)

3

p26.3-p26.2

3–5

2

26 (96%)

 

p25.3-p25.1

9–14

5

26 (96%)

9

q33.3-q34.11

128–130

2

21 (78%)

22

q13.1-q13.2

38–40

2

21 (78%)

  1. None of these regions have concomitant significant LOH (score ≥ 0.15).
  2. Abbreviations: CN, copy number; p, short arm; q, long arm; Mb, megabase.