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Table 1 List of Genes up-regulated following CPT treatment in both U87-MG and DBTRG-05 cells.

From: Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines

GeneName

Description

 

DNA-Damage and/or stress-responsive genes

ATF3

Activating transcription factor 3

CDKN1A

Cyclin-dependent kinase inhibitor 1A

DDIT3

DNA damage inducible transcript 3

DUSP5

Dual specificity phosphatase 5

EGR1

Early growth response 1

EGR3

Early growth response 3

FDXR

Ferredoxin reductase

GADD45A

DNA damage inducible transcript 1

p53CSV

p53-inducible cell-survival factor

PIG3

tumor protein p53 inducible protein 3

SAT

Spermidine/spermine N1-acetyltransferase

TIEG

TGFB inducible early growth response

TRIB3

tribbles homolog 3 (Drosophila)

 

miscellaneous

GA

Breast cell glutaminase

I_1201768

Protein of unknown function

I_928877

Protein of unknown function

I_929113

Protein with very strong similarity to ribonucleotide reductase induced by p53 (human p53R2)

IL8

Interleukin 8

KLF5

Kruppel-like factor 5 (intestinal)

PPIF

Peptidylprolyl isomerase F

SEI1

Cyclin-dependent kinase 4-binding protein

EDIL3

EGF-like repeats and discoidin I-like domains 3