Table 2 Genes down-regulated following CPT treatment in both U87-MG and DBTRG-05
GeneName | Description |
|---|---|
| Â | DNA metabolism and replication |
ADK | Adenosine kinase |
CDC45L | Cell division cycle 45 like |
DTYMK | Deoxythymidylate kinase (dTMP kinase) |
FEN1 | Flap structure specific endonuclease 1 |
H2AFZ | H2A histone family Z |
KIAA0101 | The PCNA-associated factor KIAA0101/p15(PAF) |
MCM2 | Mini chromosome maintenance deficient 2 |
MCM3 | Minichromosome maintenance deficient 3 |
MCM7 | Minichromosome maintenance deficient 7 |
RRM1 | Ribonucleotide reductase M1 subunit, |
RRM2 | Ribonucleotide reductase subunit M2, |
TYMS | Thymidylate synthetase |
UHRF1 | Nuclear protein 95 |
| Â | Cell cycle and mitosis |
ANKT | nucleolar and spindle associated protein 1 |
BIRC5 | Survivin |
CCNA2 | Cyclin A2 |
CDC2 | Cell division cycle 2 |
CDCA5 | cell division cycle associated 5 |
KNSL6 | Mitotic centromere-associated kinesin (kinesin-like 6) |
PRC1 | Protein regulator of cytokinesis 1 |
STMN1 | Stathmin 1 (oncoprotein 18) |
TOPK | PDZ-binding kinase |
UBE2C | Ubiquitin-conjugating enzyme E2C |
ZWINT | ZW10 interactor |
| Â | Miscellaneous |
DKFZp762E1312 | Protein of unknown function |
I_932099 | Protein with high similarity to human HNRPA1, |
ID1 | Inhibitor of DNA binding 1 |
KPNA2 | Karyopherin alpha 2 (importin alpha 1), |
LOXL2 | Lysyl oxidase-like 2 |
p100 | EBNA-2 co-activator (100 kD) |
SPOCK | Testican |
TSSC3 | Tumor suppressing subtransferable candidate 3 |
UBE2T | ubiquitin-conjugating enzyme E2T |