Skip to main content

Table 4 Multivariate analysis for the risk factors associated with MSI-H occurrence (Model including single term and interactions effect)

From: Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study

Factor OR (95% CI) P value
Normal hMLH1 expression by IHC 0.13(0.04–0.41) < 0.0001
BRAF V600E mutation 12.11(2.82–52.03) 0.001
hMLH1 methylation 13.84(1.05–182.72) 0.046
Race   0.946
   African-Americans 1  
   Omani 0.83(0.04–0.18.30) 0.905
   Iranian 0.68(0.07–6.58) 0.739
hMLH1 methylation* Race   0.072
hMLH1 methylation* Omani 0.04(0.01–1.74) 0.091
hMLH1 methylation* Iranian 0.02(0.01–0.63) 0.032
  1. * indicates the interaction term between two variables.