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Figure 6 | Molecular Cancer

Figure 6

From: Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer

Figure 6

Loss of SFRP2 protein expression in correlation to patient survival. (A) Univariate Kaplan-Meier analysis of patient overall survival stratified between SFRP2 expresser (IRS > 4, blue line) and SFRP2 non-expresser (IRS ≤ 4, red line). A weak association of loss of SFRP2 protein expression with unfavorable outcome could be detected (P = 0.071, two-sided log-rank test). (B) Univariate Kaplan-Meier analysis regarding disease-free patient survival. The visual impression of a clinical impact of SFRP2 protein expression loss on breast tumor recurrence was statistically not significant (P = 0.237, two-sided log-rank test). Vertical tick marks represent censored patients.

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Molecular Cancer

ISSN: 1476-4598