Methylation profiles of normal mucosa, adenomas, and carcinomas. Eleven genes were analyzed by MSP. Upper panel: non-cancerous lesions; lower panel: carcinomas stratified according to MSI-status. X-axis, the analyzed genes; Y-axis, the percentage of methylated samples. N1: normal colon samples from cancer-free individuals; N2: normal colon samples from cancer patients; MSI: microsatellite instability; MSS: microsatellite stability.