Distribution of colorectal carcinomas according to site associates with sex, age, MSI-status and methylation frequencies. The circles indicate 52 carcinomas placed according to site, the red circle = female, the blue = male. Top right section of the circle: blue = MSS, red = MSI. The lowest section: green = patient <68 years of age, yellow = patient ≥ 68 years. Widespread methylation is given in the top left section: white = methylation in < 5 genes, black = widespread methylation ≥ 5 genes.