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Table 1 Gene promoter methylation and microsatellite instability

From: Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers

 

ADAMTS1

CDKN2A

CRABP1

HOXA9

MAL

MGMT

MLH1

NR3C1

RUNX3

SCGB3A1

 

M

U

M

U

M

U

M

U

M

U

M

U

M

U

M

U

M

U

M

U

Sample type

                    

N1

0

21

0

21

0

21

4

17

1

20

2

19

0

21

0

21

0

1

1

20

N2

1

17

2

16

0

18

7

11

2

16

7

10

1

17

0

18

0

1

1

17

Adenoma

23

40

10

53

7

53

22

40

45

18

23

39

0

63

2

61

4

4

4

59

Carcinomas

36

15

17

35

25

25

12

38

41

9

21

31

11

41

13

37

16

9

9

40

MSI status

                    

Carcinomas

                    

MSI

19

8

10

17

22

5

7

20

21

6

11

16

11

16

12

15

16

8

8

18

MSS

17

7

7

18

3

20

5

18

20

2

10

15

0

25

1

22

0

1

1

22

P value

NS

NS

<0.0001

NS

NS

NS

<0.0001

0.001

<0.0001

0.026

  1. Abbreviations: M, methylated samples; U, unmethylated samples; NS, not significant; N1: non-cancerous normal samples; N2: normal samples from cancer patients. MSI status data is listed for the individual polyp. In some cases a patient may have several polyps.
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Molecular Cancer

ISSN: 1476-4598