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Figure 8 | Molecular Cancer

Figure 8

From: An MDM2 antagonist (MI-319) restores p53 functions and increases the life span of orally treated follicular lymphoma bearing animals

Figure 8

MI-319-induced FSCCL apoptotic cell death might be p53 transcription-independent. (A) FSCCL cells were treated for 12 hours and Western blotting experiments were performed to examine the protein levels of p53, MDM2, p21, Bax, PUMA and PARP. (B) FSCCL cells were grown for 24 hours after drug treatment and apoptotic cell death was assessed with Tunnel assay.

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