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Table 1 Potency (half maximal inhibition concentration) distribution of active compounds in qHTS screening

From: Identification of small molecule compounds that inhibit the HIF-1 signaling pathway

 

Number of active compounds in curve classes

IC50 (μM)

1.1

1.2

2.1

< 0.10

4

12

0

0.10-1.0

16

33

7

1.0-10.0

60

40

86

10.0-100.0

2

2

88

Total

350