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Table 2 Fold change in gene expression of selected genes regulated as a result of infection with H. pylori and/or treatment with the specific Cox-2 inhibitor NS398

From: Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo

SYMBOL GENE NAME GENE ONTOLOGY V vs V + Hp V+Hp vs NS398+Hp V vs Ns398
    6 13 19 6 13 19 6 13 19
Adn adipsin chymotrypsin, activity.
complement activation.
3.06 1.9 -1.32 -2.4 1.93 -1.07 -1.53 -2.56 -1.97
Akt3 thymoma viral proto-oncogene 3 protein amino acid phosphorylation -1.52 6.68 -1.02 -1.09 1.28 1.33 -1.44 -1.03 -1.06
AV148957 Connexin 45 water transport 1.39 -3.25 -1.04 1.29 -1.11 1.39 1 1.09 -1.01
Ccl5 chemokine (C-C motif) ligand 5 chemokine activity.
inflammatory response
1.23 -1.13 3.01 1.08 -1.13 -1.54 -1.21 1.48 1.08
Crpd. Dmbt1 deleted in malignant brain tumors 1/crp ductin, muclin scavenger receptor activity.
tumor suppressor
4.15 -3.15 7.74 -2.64 -2.09 -2.15 1.78 1.28 -1
Gast gastrin hormone activity 6.37 -1.21 1.8 -8.41 -1.87 -1.01 1 -2.35 1.45
Hsp70-3 heat shock protein 1A chaperone activity 5.3 -1.86 1.31 -5.41 1.13 -1.15 3.23 -1.35 1.11
Icsbp1 interferon consensus seq. binding protein 1 immune response; transcription regulation 1 -1.31 3.36 1.19 1.23 -1.39 1 2.04 -1.37
Ifi47 interferon gamma inducible protein ATP binding activity 1.3 -1.29 6.03 1.2 -1.13 -1.97 -1.85 -1.29 1.45
Ly75 lymphocyte antigen 75 defense response 1.23 -2.25 3.37 1.36 -1.15 1 1 1 1.39
Mup5 major urinary protein 5 pheromone binding activity; transport; transporter activity 4.94 -1.08 3 -6.56 -1.23 -2.5 7.56 -1.5 1.31
Ptgs1 prostaglandin-endoperoxide synthase 1 prostaglandin biosynthesis -1.36 -1.03 -1.02 1.16 1.03 1 1.26 1.47 1.12
Ptgs2 prostaglandin-endoperoxide synthase 2 prostaglandin biosynthesis 1.27 4.34 1.47 -1.02 1.17 1 -1.55 -1.24 -1.47
Odc Ornithine decarboxlyase carboxy- lyase activity 1.05 -1.69 -1.19 -1.34 -3.12 -1.11 1.94 -1.4 1.23
Slc7a11. cd98 light solute carrier family 7 member 11. CD98 light cationic amino acid transporter 1.37 3.42 1.19 1.09 2.24 1.33 -1.7 -1.64 -1.07
Tff1 trefoil factor 1 response to wounding -2.94 5.57 -3.06 -2.28 9.16 -1.56 -1.37 -6.56 2.84
Tgtp T-cell specific GTPase GTP binding activity 1.26 -1.24 8.29 1.55 -1.17 -2.72 -1.37 1.31 1.43
  1. The Gene Ontology (GO) classification indicates gene function. A complete list of the expression level of all genes in the study may be found in Additional File 1, Tables S1-3.