Table 2 Fold change in gene expression of selected genes regulated as a result of infection with H. pylori and/or treatment with the specific Cox-2 inhibitor NS398
From: Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo
SYMBOL | GENE NAME | GENE ONTOLOGY | V vs V + Hp | V+Hp vs NS398+Hp | V vs Ns398 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | 6 | 13 | 19 | 6 | 13 | 19 | 6 | 13 | 19 |
Adn | adipsin | chymotrypsin, activity. complement activation. | 3.06 | 1.9 | -1.32 | -2.4 | 1.93 | -1.07 | -1.53 | -2.56 | -1.97 |
Akt3 | thymoma viral proto-oncogene 3 | protein amino acid phosphorylation | -1.52 | 6.68 | -1.02 | -1.09 | 1.28 | 1.33 | -1.44 | -1.03 | -1.06 |
AV148957 | Connexin 45 | water transport | 1.39 | -3.25 | -1.04 | 1.29 | -1.11 | 1.39 | 1 | 1.09 | -1.01 |
Ccl5 | chemokine (C-C motif) ligand 5 | chemokine activity. inflammatory response | 1.23 | -1.13 | 3.01 | 1.08 | -1.13 | -1.54 | -1.21 | 1.48 | 1.08 |
Crpd. Dmbt1 | deleted in malignant brain tumors 1/crp ductin, muclin | scavenger receptor activity. tumor suppressor | 4.15 | -3.15 | 7.74 | -2.64 | -2.09 | -2.15 | 1.78 | 1.28 | -1 |
Gast | gastrin | hormone activity | 6.37 | -1.21 | 1.8 | -8.41 | -1.87 | -1.01 | 1 | -2.35 | 1.45 |
Hsp70-3 | heat shock protein 1A | chaperone activity | 5.3 | -1.86 | 1.31 | -5.41 | 1.13 | -1.15 | 3.23 | -1.35 | 1.11 |
Icsbp1 | interferon consensus seq. binding protein 1 | immune response; transcription regulation | 1 | -1.31 | 3.36 | 1.19 | 1.23 | -1.39 | 1 | 2.04 | -1.37 |
Ifi47 | interferon gamma inducible protein | ATP binding activity | 1.3 | -1.29 | 6.03 | 1.2 | -1.13 | -1.97 | -1.85 | -1.29 | 1.45 |
Ly75 | lymphocyte antigen 75 | defense response | 1.23 | -2.25 | 3.37 | 1.36 | -1.15 | 1 | 1 | 1 | 1.39 |
Mup5 | major urinary protein 5 | pheromone binding activity; transport; transporter activity | 4.94 | -1.08 | 3 | -6.56 | -1.23 | -2.5 | 7.56 | -1.5 | 1.31 |
Ptgs1 | prostaglandin-endoperoxide synthase 1 | prostaglandin biosynthesis | -1.36 | -1.03 | -1.02 | 1.16 | 1.03 | 1 | 1.26 | 1.47 | 1.12 |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | prostaglandin biosynthesis | 1.27 | 4.34 | 1.47 | -1.02 | 1.17 | 1 | -1.55 | -1.24 | -1.47 |
Odc | Ornithine decarboxlyase | carboxy- lyase activity | 1.05 | -1.69 | -1.19 | -1.34 | -3.12 | -1.11 | 1.94 | -1.4 | 1.23 |
Slc7a11. cd98 light | solute carrier family 7 member 11. CD98 light | cationic amino acid transporter | 1.37 | 3.42 | 1.19 | 1.09 | 2.24 | 1.33 | -1.7 | -1.64 | -1.07 |
Tff1 | trefoil factor 1 | response to wounding | -2.94 | 5.57 | -3.06 | -2.28 | 9.16 | -1.56 | -1.37 | -6.56 | 2.84 |
Tgtp | T-cell specific GTPase | GTP binding activity | 1.26 | -1.24 | 8.29 | 1.55 | -1.17 | -2.72 | -1.37 | 1.31 | 1.43 |