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Figure 3 | Molecular Cancer

Figure 3

From: Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

Figure 3

Chemopreventive activity of ATRA in the 2-stage model. A, Tumor multiplicity for mice in the 2-stage skin carcinogenesis experiment. Tumors were counted weekly. Error bars represent +/- SEM for each treatment group (n = 5). B, H&E stain of paraffin sections from representative tumors isolated from mice in the TPA alone and TPA+ATRA 30 week treatment groups. Magnification = 200×. C, IHC staining of serial sections from the same tumors with an antibody to cytokeratin 10 followed by an Alexa-488-labeled secondary antibody and counterstaining with DAPI. Magnification = 600×.

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Molecular Cancer

ISSN: 1476-4598