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Figure 5 | Molecular Cancer

Figure 5

From: Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

Figure 5

TPA does not induce p38 and JNK phosphorylation. A. Paraffin sections of SENCAR mouse skin treated for 7 weeks with Acetone (Control), TPA, TPA+ATRA, and ATRA alone were probed with phospho-p38 and phospho-JNK antibodies followed by an Alexa-546-labeled secondary antibody and DAPI counterstain. All panels in A were photographed at 600× magnification. B. Western blots were run as in Fig. 4E for 7 week epidermal lysates and probed with antibodies for total p38, phospho-p38 (p-p38), total JNK, phospho-JNK (p-JNK) and β-actin.

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