Figure 7
From: Corticotropin Releasing Factor promotes breast cancer cell motility and invasiveness
CRF induces the expression of Cox-1 and the production of prostaglandins. A. MCF7 cells were treated with CRF (10-8 M) or vehicle (control) for 6 and16 hours and total prostaglandin production in the supernatant was measured by ELISA; ***p < 0.001; Results represent the average of three independent experiments. B. MCF7 cells were treated with CRF (10-8 M) for 3, 6 and 24 hours and Cox-2 was measured by western blot. C. MCF7 cells were treated with CRF (10-8 M) for 6, 12 and 24 hours and Cox-1 was measured by western blot. Results are representative of three independent experiments.