Figure 1
From: Identification of novel Notch target genes in T cell leukaemia
Affymetrix microarray array analysis of Notch1-transduced Jurkat cells. Jurkat cells were transduced with GFP-alone, N1ΔE, or N3ΔE retrovirus and after 48 hrs, GFP+ cells were isolated by flow cytometry and total RNA extracted for Affymetrix array analysis. Data presented represents mean of 4 independent experiments. Graphical representation of microarray data showing the 15 genes most upregulated by Notch1. * represents p < 0.05 vesus GFP-alone-transduced cells based on p-values from n = 4 experiments. Using false discovery rate analysis, none of these changes were significant.