Figure 2From: Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafishZebrafish tumors induced by co-expression of zebrafish Smoa1 and constitutively active human AKT1. A, B and C, a 12-week-old fish with rhabdomyoma (A), showing GFP expression exclusively in the tumor (B); D, E and F, a 6-week-old fish with glioblastoma; G, H and I, a 8-week-old double transgenic fish with astrocytoma in the lower trunk region. Scale bars, 50 μm.Back to article page