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Figure 3 | Molecular Cancer

Figure 3

From: Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)

Figure 3

1H-13C 2-D HSQC identification of 13C-metabolites in the TCA extracts of lung tumor tissues of patient #6. Metabolites were identified based on 1H-13C covalent linkages observed in the 2-D contour map (panel B) and from the TOCSY spectrum such as in Fig. 2B. Panel A is the 1-D projection spectrum of the 2-D data along the 13C dimension, which allows a better comparison of the peak intensity of different metabolites. Panel C displays the expanded spectral region of C3 and C4 resonances of Glu, Gln, and GSSG-Glu to illustrate the resolution of these resonances in the 2-D HSQC contour map.

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