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Table 1 Effect of EF1α downregulation and pAkt inhibition on cell cycle distribution of HCC1937 cells

From: Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility

Cells

G0/G1

S

G2/M

Apoptosis

CTRLsiRNA

60

18.8

20.3

1,8

EFsiRNA

69.4

10.5

17.2

5

CTRLsiRNA + inhib.

63.3

18.8

15.8

4.6

EFsiRNA + inhib.

77.5

10.5

7.6

6.4

  1. Representative of three different experiments with similar results. Values indicate % of cells in different cell cycle phases and apoptosis.
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Molecular Cancer

ISSN: 1476-4598