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Figure 2 | Molecular Cancer

Figure 2

From: Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy

Figure 2

Effect of celecoxib on p53 protein expression and localisation. U87MG and U87MG-E6 cells were analysed for basal p53 expression (A). U87MG and LN229 cells were treated with celecoxib (18 hours), followed by immunoblotting for detection of p53. β-actin was used as loading controls. p53 expression is presented normalised over β-actin of same samples. C, controls; 8 and 30, treated with celecoxib 8 and 30 μM, respectively (B, n = 4–5). Representative images of celecoxib-treated (18 hours) U87MG cells immunostained with anti-p53 FITC and DAPI are shown (C, n = 3).

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Molecular Cancer

ISSN: 1476-4598