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Figure 7 | Molecular Cancer

Figure 7

From: Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action

Figure 7

Effects of BER on mRNA expressions of MMP-2 and MMP-9 in MDA-MB-231 cells. The mRNA expressions were determined by semi-quantitative RT-PCR after the cells were treated for 16 h with BER at 0 (control), 40 μM and 60 μM. mRNA expression level was normalized to β-actin. For one experiment, 3 assays were carried out and only one set of gels is shown. The density of the band (normalized to β-actin) shown as mean ± SD is relative to that of the control (designated as 1.00). Statistical analysis was done using the ANOVA and Bonferroni test. Significant decreases in the mRNA expressions were observed in MMP-2 (n = 3) and MMP-9 (n = 3). **, P < 0.01, significant difference.

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