Molecular Cancer

Table 2 Association of rs6983267 with MYC expression in colon tissue

From: No effect of cancer-associated SNP rs6983267 in the 8q24 region on co-expression of MYC and TCF7L2 in normal colon tissue

factors	*MYC* assay 1, p-value *	*MYC* assay 2, p-value *
^ars6983267	0.85	0.91
^bage	0.040	0.043
^brs6983267	0.83	0.84
age	0.13	0.13
Rs6983267	0.85	1.00
TCF7L2 TSS1	0.054	0.076
rs6983267*TCF7L2 TSS1	0.91	0.91
age	0.069	0.062
Rs6983267	1.00	0.97
TCF7L2 ex3a-4	0.36	0.52
rs6983267*TCF7L2 ex3a-4	0.93	0.77
Age	0.31	0.39
Rs6983267	0.75	0.28
TCF7L2 ex7-8	0.0039	0.021
rs6983267*TCF7L2 ex7-8	0.79	0.25
age	0.045	0.037
Rs6983267	0.95	0.90
TCF7L2 ex11-13a	0.31	0.50
rs6983267*TCF7L2 ex11-13a	0.97	0.89
age	0.38	0.37
Rs6983267	0.70	0.61
TCF7L2 ex11-14	0.0008	0.013
rs6983267*TCF7L2 ex11-14	0.57	0.50
age	0.13	0.19
Rs6983267	0.22	0.41
TCF7L2 ex11-13	<0.0001	<0.0001
rs6983267*TCF7L2 ex11-13	0.29	0.48
age	0.25	0.27
Rs6983267	0.28	0.30
TCF7L2 ex13-14	<0.0001	<0.0001
rs6983267*TCF7L2 ex13-14	0.35	0.35

*p-values for univariate regression analysis including 0, 1 and 2 alleles of rs6983267 and expression of MYC assays 1 and 2 in the presence of covariates -- age and level of expression of TCF7L2 assays or interaction between rs6983267 and TCF7L2 expression; p-values are not adjusted for multiple tests; ^a genotypes were available for 96 samples; ^b age and genotypes were available for 79 samples.

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