Figure 5From: Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitroEffect of IGFBP3 overexpression on GIST-T1 cell sensitivity to imatinib. GIST-T1 cells were mock infected or infected with indicated titers (moi) of Ad-IGFBP3 or Ad-EV. The following day, infected cells were exposed to imatinib (0.075 μM) for 48 hours. Viability was assessed with the MTS assay. NS, not significant.Back to article page