Figure 4From: Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patientsHypothesis scheme of Smad influence on survival. TGFβ1 upregulation is associated with tumor agressiveness and poor patient survival. Smad2 and Smad6 have opposite roles in this process. Full and dashed lines represent our own findings and previous published data, respectively.Back to article page