Table 3 Gene ontology of common down-regulated genes.

Cellular metabolism (31.6%)

NM_030965

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

3943.41

NM_022969

fibroblast growth factor receptor 2

684.03

AU152837

Sal-like 1 (Drosophila)

312.29

NM_007287

membrane metallo-endopeptidase

73.38

BF589322

R-spondin 3 homolog (Xenopus laevis)

70.16

Signal transduction (17.8%)

NM_001200

bone morphogenetic protein 2

68.96

NM_000710

bradykinin receptor B1

48.96

R72286

microfibrillar-associated protein 4

32.40

NM_004114

fibroblast growth factor 13

28.15

BE218107

EPH receptor A5

25.68

Transcription factor (11.5%)

AJ277914

LIM homeobox 9

25.01

NM_001452

forkhead box F2

18.08

AA705845

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

17.16

BG261252

ecotropic viral integration site 1

11.58

NM_020327

activin A receptor, type IB

9.32

Protein modification (7.9%)

AF245505

matrix-remodelling associated 5

57.89

AA725644

ubiquitin specific peptidase 42

18.73

NM_001982

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

11.34

AV727260

protein tyrosine phosphatase, receptor type, D

10.93

NM_002570

proprotein convertase subtilisin/kexin type 6

9.83

Cell differentiation (6.2%)

NM_000641

interleukin 11

17.51

BC006454

growth arrest-specific 7

15.20

M69148

midkine (neurite growth-promoting factor 2)

14.03

NM_003991

endothelin receptor type B

10.85

AI758962

EPH receptor A4

7.15

Cell adhesion (5.9%)

NM_001999

fibrillin 2

1035.17

NM_014893

neuroligin 4, Y-linked

68.62

AI694562

collagen, type IV, alpha 3

22.21

NM_005864

embryonal Fyn-associated substrate

8.44

AU146651

collagen, type XII, alpha 1

4.89

Cell cycle (5.9%)

NM_014059

chromosome 13 open reading frame 15

28.40

M19701

retinoblastoma 1 (including osteosarcoma)

4.93

NM_002009

fibroblast growth factor 7

4.44

NM_014703

Vpr (HIV-1) binding protein

3.92

AI983033

DEAD/H box polypeptide 12

3.91

Cell motility (4.7%)

NM_002784

pregnancy specific beta-1-glycoprotein 9

69.22

X99268

twist homolog 1

5.45

NM_015180

spectrin repeat containing, nuclear envelope 2

3.81

AI990816

laminin, alpha 1

3.59

N90777

neuropilin 2

3.57

Cell proliferation (4.5%)

NM_016931

NADPH oxidase 4

5.79

AF064826

glypican 4

4.31

NM_004525

low density lipoprotein-related protein 2

3.85

NM_001963

epidermal growth factor (beta-urogastrone)

3.70

AF064103

CDC14 cell division cycle 14 homolog A

3.67

Apoptosis (4.0%)

NM_006850

interleukin 24

25.27

NM_002135

nuclear receptor subfamily 4, group A, member 1

5.48

NM_003823

tumor necrosis factor receptor superfamily

4.59

AJ301610

glutamate receptor, ionotropic, kainate 2

3.92

NM_005809

peroxiredoxin 2

3.90