Figure 2

Schematic Figure of Wild Type EGFR Domains and Subdomains. This figure shows the number of exons, amino acids, and nucleotides in each domain. Arrows correspond to selected primers used to identify wild type EGFR and EGFR isoforms. Numbers below the arrows match the location of the primers on EGFR RNA sequence (accession#NM_005228). Names between arrow pairs correspond to the name of the primer set; Xcell and Intracell specify sequences encoding the extracellular and intracellular domains of EGFR (see Table 1).