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Figure 3 | Molecular Cancer

Figure 3

From: Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition

Figure 3

E-cadherin expression suppresses migration (A) and invasion (B). Cell migration was analyzed using a scratch assay. Scratch closure was measured over a period of 24 hours and the fraction closure was quanitified by Metamorph software (n = 3). Invasion was measured in using a Matrigel invasion assay in which cells were allowed to migrate through a Matrigel-coated transwell insert for a period of 24 hours. N = 3 in triplicate; mean ± s.e.m. Results shown are representative of one of two independent clones of each mutant.

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