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Table 1 Effective drug doses for nelfinavir-mediated cell death [μg/ml]

From: The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization

 

HL60

Jurkat

IM9

BMC

ED50

5.6

5.8

7

15.2

ED80

8.9

7.8

9.3

23

ED90

9.8

9

10

N.D.

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Molecular Cancer

ISSN: 1476-4598